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D-Sight


dsight
  • High-quality scanning sensor 
  • Integrated 1D/2D barcode reader
  • Digital microscope for real-time live slide viewing
  • Remote digital microscope
  • Optional Images Analysis modules
  • Web application
 

Features

Features

D-Sight is an automated brightfield digital slide microscope and scanner that allows fast and reliable acquisition, navigation, analysis, archiving and sharing of high quality digital images. Entire slides can be scanned at selectable magnifications with high focus precision and excellent image quality. D-Sights dedicated Web application provides unlimited remote access to acquired images and password-protected access to individual files and working environments..

  • Digital microscope for live mode slide browsing and remote digital microscope
  • 8-slide capacity
  • Motorised revolver with up to 7 high-resolution objectives and high-quality scanning sensor
  • Various hardware profiles (H&E, IHC, haematology, cytology)
  • Two scanning speeds and Z-stacking
  • Selectable magnifications
  • Measuring, mark-up and text tools
  • Analysis modules for membrane, nuclei, tissue microarray, FISH amplification, FISH translocation, FISH Spot counting and immunofluorescence
  • Optional Enjoy ambidextrous joystick for navigating images
  • Optional macro section slide tray

Image analysis software modules

Image analysis software modules

Pathology images contain embedded prognostic data that may not be apparent to a pathologist. Mining these subtle features can provide better quantitative modelling to improve prediction of disease aggressiveness, patient outcomes and even response to specific targeted therapies. Menarini’s algorithms enhance overall system functionality through computer-assisted quantitative slide analysis to support treatment decisions with objective data and bring patient safety to the forefront.

For each one of the available tools it is possible:

  • The customisation of the analysis with the definition of new dedicated analysis profiles
  • The selection of regions of interest of analysis at various magnifications and the possibility, within the same fields, include / exclude regions.
  • Processing of multiple regions within the same image automatically accumulating the partial results into one final result.

 

Brightfield Analysis Module

Membrane analysis module:

brightfield
The membrane analysis module can be used for identification and semi-quantitative scoring of HER2 IHC staining; 4 scoring classes are available (0, 1+, 2+, 3+). For each processed image, the system provides an opinion based on the intensity and completeness of membrane staining for every tumour cell, as well as their overall percentage in the histological sample.
Results are presented graphically, by highlighting membranes with colours that correspond to the degree of positivity, and numerically, using the percentage of cells in each class. Results can be printed and added to the case report.

 

IHC Nuclei analysis:

brightfield 2
Nuclei analysis module can be used foridentification and semi-quantitative scoring of oestrogen receptor (ER), progesterone receptor (PR) IHC staining (four scoring classes: 0, 1+, 2+, 3+) and the Ki-67 proliferation marker. For each processed image, the system provides an assessment based on nuclear morphology and staining.
Results are presented graphically, by highlighting the nuclei with colours that correspond to the degree of positivity, and numerically, using the percentage of nuclei in each class.

 

Tissue Micro Array (TMA) module:

The Tissue Micro Array (TMA) analysis is an application to identify and visualise several patient’s spots. TMA are used to have in a single slide micro-quantity of tissue coming from different samples (tissue /patients). In each slide the tumour specimens are inserted in a new matrix that allows identifying each different spot in a univocal manner. During spot-patient association, the system automatically identify all the spots and loads, from external file (.xls), all the patient's information  and it directly associated with the found spot. Using virtual spots’ browsing is possible both: view spots inserted in the slide and all the data extract from the external Excel file, and make searches

Web server interface (NAVIWEB)

Web server interface (NAVIWEB)

naviweb 3

naviwebThe NAVIWEB web-based application makes NAVIGO/D-Sights the ideal solution for telepathology, providing access to digitised slides from anywherewith immediate image display and navigation. Once the acquired images are uploaded to a web-server, they can be accessed at any time from any web-device. Different user with access rule and permission can be created. Each scanned slide can be loaded (automatically) in a web server and will be available for navigation. The internet browser can be used to view images with a series of interactive tools. NAVIWEB has an online archive where upload digital images generated by one or more systems NAVIGO/D-Sights connected to the server machine, and through a web interface, it allows the navigation of the slides. NAVIWEB is a solution of remote working for the pathologist, to view scanned images, create work projects, provide and receive telepathology services.

  • No software to download or installnaviweb 2
  • Seamless multi-user sharing of digital slides
  • Fast image streaming and instant notification to remote users when a case is assigned for
  • Review or real-time consultation
  • Simultaneous examination of sample images and synchronised navigation
  • Easy navigation with the image viewer

Downloads

Downloads

Smart Digital Pathology Brochure

Technical Specifications

Technical Specifications

Reference 49467
Slides 8 slides automatic
Objective 4x, 10x, 20x, 40x
Number of objectives Up to 7
Scanning magnification 4x, 10x, 20x, 40x
Scanning speed (1 cm2 Brightfield) Speed Mode: 4x <10 sec, 20x <2 min, 40x <6 min
Precise Mode: 4x <10 sec, 20x <3 min, 40x <12 min
Resolution at 20x 0.5 µm/pixel
Resolution at 40x 0.25 µm/pixel
Image compression Jpeg2000
Compression level (brightfield) 1x1cm a 20x ≈ 80MB (not compressed ≈ 1GB)

1x1cm a 40x ≈ 140MB (not compressed ≈ 4GB).

Barcode reader Yes
Illumination LED
Digital microscope acquisition Yes
Optional accessories Monitor 24” Full HD, Enjoy joystick
Image analysis modules IHC Analysis module, IHC Membrane, IHC Nuclei, TMA
LIS connection Yes
Web application Optional (NAVIWEB)

 Environmental Conditions - Working Session

Temperature 10-40° C
Relative Humidity 8-75% RH (no condensate)

 Electrical Specifications

Power Source AC 100-240V 50/60 Hz

Size

Microscope Unit (HxWxL) 60 x 60 x 40 cm
Processing Unit (HxWxL) 46 x 52 x 21 cm
Display Unit 24" (HxWxL) 46 x 25 x 57 cm

Weight

Microscope Unit 30kg
Processing Unit 15kg
Display Unit 10kg